K9 Advantix II Flea, Tick & Mosquito Protection - 4 Doses

Who is this product for?

K9 Advantix II is a monthly broad-spectrum topical treatment for dogs and puppies 7 weeks and older, weighing 1.4 kg (3 lbs) or more. It is one of the most comprehensive parasite preventatives on the market, recommended by veterinarians. The 4-dose pack offers four months of continuous protection — an excellent balance between price and commitment, ideal for covering the summer season in Quebec. It is particularly suitable if you are looking for:

• Comprehensive 5-target protection — fleas, ticks, lice, mosquitoes, and stable flies
• Lyme disease protection — kills deer ticks (Ixodes scapularis), the primary vector of Lyme disease in Quebec, where cases have been sharply increasing since 2020
• Pre-bite preventative action — parasites die on contact with the skin, without needing to bite your dog
• Water-resistant formula that remains effective after shampooing, bathing, or swimming
• Repellent effect against mosquitoes and stable flies, which can transmit diseases
• Simple and quick application — just one application per month
• A pack that covers the entire risk season — 4 months of protection, ideal for April to July or August to November

Active ingredients

• Imidacloprid 8.8% — kills adult fleas on contact by interfering with their nervous system
• Permethrin 44% — repels and kills ticks, mosquitoes, and stable flies. ⚠️ This ingredient is toxic to cats — never use on a cat.
• Pyriproxyfen 0.44% — growth regulator that prevents the development of flea eggs and larvae

Mode of action

K9 Advantix II is applied to the skin, along the dog's back. From there, it spreads evenly in a thin layer over the skin surface and adheres to the sebum, rather than being absorbed into the bloodstream.

When parasites like fleas, ticks, mosquitoes, or lice come into contact with the treated dog's skin, their nervous system is immediately affected. The parasites quickly lose coordination and die — without needing to bite your dog. This protects your pet from the discomfort of bites and can help prevent the transmission of diseases like Lyme disease, heartworm, or anaplasmosis.

Dose selection by weight

Instructions for use

1. Remove one tube from its packaging and hold it upright, tip facing up
2. Break off the tip of the tube by bending it
3. For dogs under 11 kg: apply the entire contents of the tube to the base of the neck, between the shoulder blades
4. For dogs over 11 kg: apply the contents at 3 or 4 spots along the back, from the base of the neck to the base of the tail, parting the hair to reach the skin
5. Allow to dry completely (approximately 24 hours) before wetting, bathing, or allowing another animal to touch your dog
6. Repeat application once a month for continuous protection

🚨 Critical precautions for households with cats

Important precautions

• External use only — do not ingest
• For dogs 7 weeks and older only, weighing 1.4 kg (3 lbs) or more
• Never use on a cat or rabbit — permethrin is toxic to these species
• Avoid contact with your dog's eyes and mouth
• Wash your hands after application
• Keep out of reach of children
• Avoid direct contact with the product for 24 hours after application
• Slight local irritation may occur; it usually resolves quickly
• Discontinue use and consult a veterinarian if you observe unusual signs (excessive salivation, lethargy, tremors, seizures, loss of appetite)
• Do not use on sick, weakened, or elderly dogs without veterinary advice

Package contents

4 doses = 4 months of treatment. Each box contains 4 pre-dosed single-use tubes.

💡 Economic tip: the 4-dose pack costs approximately $22.05 per monthly treatment for small dogs ($24.75 for large dogs), a saving of about 18% compared to the 2-dose pack. This is an excellent choice to cover the summer season in Quebec.

Other formats available

• 2-dose pack (2 months) — ideal for trying the product or for occasional protection (short summer season, travel to tick-prone areas, forest hiking)

Seasonal recommendation in Quebec

In Quebec, the tick season generally runs from March to November, but can start as soon as the temperature exceeds 4 °C. For optimal protection against Lyme disease, it is recommended to continuously treat your dog during this period, especially if you frequent forests, hiking trails, dog parks, or rural areas.

The 4-dose pack ideally covers May to August (peak tick activity) or August to November (second wave of autumn activity).

Storage

Store at room temperature, away from direct sunlight and excessive heat. Keep out of reach of children and animals.

Important notice: The information provided on this page is for informational purposes only and does not replace veterinary advice. If in doubt or if your dog has health problems, consult your veterinarian before using this product.